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Bespar review
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Bespar, an effective medication for moderate anxiety, is different from traditional benzodiazepines and has the advantage of having no sedating effects. Patients may start relying on the medication for treatment of mild symptoms after realizing the other possible effects and interactions.
Bespar is an antianxiety medication that targets serotonin type 1A receptors. Serotonin is a chemical in the brain responsible for the patient’s mood so as the medication alters the messages passed on by the neurotransmitter, anxiety can be alleviated. Bespar is available by the brand names Buspimen, Narol, Sorbon, Buspar or Buspar Dividose and is available in tablet form. Bespar does not cause the patient to feel sedated which is unlike other antianxiety medications belonging to the benzopiazepine class.
Bespar is given to patients who have anxiety disorders and provides short-term relief of anxiety symptoms. It is effective for individuals with generalized anxiety in moderate cases. Severe anxiety, panic disorders and obsessive-compulsive disorders may be treated with this medication, but not as well as compared to other antipsychotic medications.
Bespar can cause some side effects with varying intensities. Included in these side effects are drowsiness, upset stomach, stomach pain, diarrhea, constipation, headache, depression, excitement, insomnia, lightheadedness, weakness or numbness, chest pain, confusion, soar throat, ringing in the ears, nervousness and fatigue. Seek immediate medical attention if you experience symptoms such as skin rash, vomiting, itching, arrhythmia, unusual head or neck muscle movement and blurred vision.
Special precautions should be taken with patients suffering from or with a history of kidney or liver disease. Bespar is contraindicated for people who have known hypersensitivity reactions to this or other medications or food.
Women who are pregnant, plan to become pregnant and breastfeeding mothers should first consult their doctor before taking this medication. Children should be monitored carefully to ensure proper treatment.
Talk with your doctor about possible interactions if you intend to consume alcohol or caffeinated beverages while taking this medication. It is possible that these will affect the medication’s efficiency.
Bespar is believed to interfere with serotonin function in the brain through its partial agonistic action on the 5-HT1A receptor. It also has agonist and antagonistic actions on dopamine receptors and some indirect actions on other chemicals in the brain. As serotonin and dopamine levels are improved, people suffering from anxiety will experience relief and relaxation.
In a study, 30 patients with moderate anxiety were given 10 mg of Bespar twice a day for 2 weeks. These patients were not given any antipsychotic medications prior to treatment. After the first week, 24 patients showed signs of improved mood and relief. Within the second week, 28 out of 30 patients were considered emotionally stable while the other two improved from moderate to mild anxiety.
Bespar is available in pharmacies and doctor’s clinics. Be sure to check the expiration date, manufacturer and location of manufacturer. When buying online, verify the source first to be confident about the quality and freshness of the medication.
The usual recommended dosage for Bespar is 10 mg to 15 mg two to three times daily. Since it is less potent than benzodiazepines, benzodiazepines are usually given first. Bespar works well when co-prescribed with benzodiazepines for patients with social phobias and panic attacks.
Bespar has the following structural formula:
- Molecular formula of bespar is C21H31N5O2
- Chemical IUPAC Name is 8-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-8-azaspiro[4.5]decane-7,9-dione
- Molecular weight is 385.503 g/mol
- Bespar available : 5mg tablets, 7.5mg tablets, 10mg tablets, 15mg tablets, 30mg tablets
Source: Medicalook.com
